Synbiosis has launched its next generation Ames software module featuring a time-saving Ames mutagenicity ratio calculation function.
The new software, designed for integrated use with the ProtoCOL 3 colony counter, facilitates rapid production of accurate, consistent, count and ratio data from Ames test plates and is suitable for use in regulated toxicology testing laboratories.
Product features:
Enables ProtoCOL 3 to quickly count Salmonella typhimurium or E.coli colonies cultured on, for example, Vogel Bonner medium before and after exposure to potentially toxic or non-toxic control compounds.
Automatically compares the different colony counts to generate an Ames mutagenicity ratio, providing a quick guide to the mutagenic potential of a test chemical. Ratio results are objective as they are not dependent on the scientist performing the tasks.
Produces full-colour images of Ames test plates which can be stored in a secure SQL database for reference and another count, if required.
Count and ratio data can be automatically downloaded to a spreadsheet (Excel/ OpenOffice) or LIMS, thus eliminating data transfer errors, to generate reproducible, traceable results, which are consistent from one microbiologist to another.
Ames software is GLP compliant and can be used in a 21 CFR Part 11 environment.
Kate George, Sales and Technical Director at Synbiosis, said: “Manually calculating the Ames mutagenicity ratio by comparing different sets of colony counts is a common approach for determining if a compound is mutagenic, but it is time-consuming and can be prone to human error.
“Our new module with its ratio calculation function is a time-saving solution to this problem and makes the ProtoCOL 3 and integrated Ames software an intelligent choice for any toxicology testing laboratory.”
Users with Ames software licences for ProtoCOL 3 can download the upgrade free of charge at: https://www.synbiosis.com/support/software-downloads/
