Waters has introduced Acquity Ultra Performance Liquid Chromatography (UPLC) and HPLC columns for separations using acidic, low-ionic-strength mobile phases
The columns offer method-development scientists additional selectivity choices and improved chromatographic performance.
The three new chemistries will be available in fully scalable UPLC, HPLC and preparative columns and particle sizes.
The Acquity CSH and Xselect HPLC columns feature Charged Surface Hybrid (CSH) technology - the CSH C18, CSH Fluoro-Phenyl and CSH Phenyl-Hexyl chemistries.
These UPLC and HPLC columns offer sharp peak shapes for basic compounds, fast column re-equilibration after mobile-phase pH changes and improved batch-to-batch reproducibility for ionised compounds in acidic mobile phases.
Waters' Acquity CSH and XSelect HPLC columns are available in 1.7 (UPLC), 3.5 and 5um (HPLC) particles, and are suitable for HPLC and UPLC methods developed on the Waters Acquity UPLC H-Class System, equipped with Fusion Method Development software from S-Matrix.
The CSH Technology-powered columns feature high-mass loading capacity for basic compounds and the ability to seamlessly scale separations between UPLC, analytical HPLC and preparative HPLC platforms.
Xselect preparative HPLC columns utilise Waters patented Optimum Bed Density (OBD) column hardware (up to 50mm internal diameter) for long, predictable preparative column lifetimes.