Harvard Apparatus-Hugo Sachs Electronik has introduced its Aerosol Exposure Unit (AEU) for mice and rats, which is suitable for exposing groups of mice or rats to aerosolised powders or liquids.
This is Harvard Apparatus-Hugo Sachs Electronik's first system dedicated to inhalation studies in awake animal models.
The AEU is a compact system that works with up to four mice or four rats at a time.
The advantage of this system is that the animals remain awake and metabolic functions are not affected by anesthesia.
Researchers also have the option of using this system with dry powders or soluble aerosols.
With the addition of data analysis software, HSE Pulmodyn, the researcher can also measure respiratory parameters, such as tidal volume; maximum inspiratory and expiratory flow; respiration rate; duration of inspiration and expiration; apnea time; time of brake and time of pause; and airflow at 0.5TV.
The AEU system is suitable for toxicology studies where a precise understanding of dosage is required.
It also caters for high-throughput drug studies when working with aerosolised substances.
The controlled delivery system is also useful for reducing unknowns when working on bioavailability studies.
The AEU is a modular system and Harvard Apparatus is available to configure it for the researcher's specific needs.
