Signal enhancing lens boosts confocal laser scanning microscopy system to permit imaging of live cells at low laser powers for increased sample viability
Bio-Rad Cell Science Division is adding a live cell option to its CellMap ID and CellMap IC low-cost confocal laser scanning microscopy systems.
The move is a breakthrough for researchers on a limited budget who require high quality images of live cells and, to mark the occasion, Bio-Rad is giving the first 25 purchasers a free Dell Axim pocket PC.
The live cell option consists of a unique signal enhancing lens system (Sels) that permits imaging of live cells at low laser powers for increased sample viability.
It also includes TimeCourse software, providing real-time observation of signal intensities over time.
CellMap ID and CellMap IC are the first two models in a family of products designed specifically for researchers on a low budget.
Without compromising image quality or sensitivity they offer features previously restricted to more expensive systems, including optical sectioning of samples in three dimensions and over time, unique fast sequential image acquisition that eliminates fluorophore cross-talk and retro-fitting to existing microscopes. Based exclusively on reliable solid state lasers, CellMap is small enough to sit on the average desk or bench top and is ideal for individuals who want two-colour confocal imaging.
The system also boasts intuitive, easy to use software to acquire images and measure fluorescence CellMap ID (blue-green) offers a 405nm and a 488nm solid state laser.
Applications include dual colour imaging of Dapi stained nuclei and FITC or GFP stained proteins.
The system is capable of viewing photo-activateable GFP and, with a bright TRITC or Cy3 conjugate, it is possible to image three fluorophores with this two-laser system.
CellMap IC (green-red) offers a 488nm and a 532nm laser to image FITC or GFP in combination with common red fluorophores such as TRITC or Cy3. The applications for this system are extensive, ranging from pathology to identifying novel proteins in brain slices.
