New applications to manage and analyze biological assay data for lead optimization are now available to biotechology, pharmaceutical, and chemical researchers
BioAssay HTS and BioSAR Browser applications to catalogue, mine, and analyze bioassay data are based on CambridgeSoft's ChemOffice WebServer, a web-based scientific application development and deployment system that works with standard internet communication protocols, leading storage systems such as Oracle Cartridge and SQL Server, and other enterprise information systems.
BioAssay HTS offers scientists an effective means of managing test results from bioassay and other experiments intended to assess biological efficacy.
Suitable for both plate-based high throughput screening (HTS) assays and smaller-scale lead optimization experiments, BioAssay HTS provides simple tools to set up models, upload data, automate calculations, and report results.
BioSAR Browser is a data-dictionary driven structure-activity analysis program that allows researchers to share their analysis methods.
Once an assay is registered in the data dictionary, it can be made available to others.
Highly granular security and role-based operations allow scientists to add new analyses, create and publish reports, or simply use methods and results prepared by others.
This application also includes ChemDraw for Spotfire, a powerful chemistry-aware add-in for the SpotFire DecisionSite software.
These Applied BioInformatics solutions complement CambridgeSoft's other major research information applications: Knowledge Management includes the E-Notebook Enterprise, Document Manager, Discovery Lims, and 21CFR11 Compliance applications to organize the records and documents of a research organization.
Research and Discovery applications include a Registration System, with an optional Formulations and Mixtures capability; Inventory Manager, for life-cycle tracking of chemicals; and CombiChem Enterprise, for the generation and management of combinatorial chemical libraries.
Chemical Databases provide reference information about chemical availability, properties, and reactions.
They include CambridgeSoft's licensed electronic implementations of the well-known Merck Index (see separate press release) and Organic Syntheses.
The ChemACX database lists commercially available chemicals from 300 suppliers, while ChemIndex provides property information for thousands of common chemicals.
