Sydney IVF completed a successful trial of the MethylEasy DNA bisulphite modification kit from Human Genetic Signatures in 2004
During the trial, Sydney IVF was able to achieve excellent detection of methylated cytosine residues starting from as little as 60 cells - around 400 picograms.
Sydney IVF is studying methylation patterns as part of an overall project aimed at understanding the impact of these patterns on embryonic development.
In the pipeline, due for release in early 2005, is a high throughput version of the MethylEasy technology.