Shimadzu poster evaluates Fourier transform infrared (FTIR) microscopy: packaging, integrity, contamination, and stability (Pics) analysis of solid formulations in the pharmaceutical industry
Shimadzu Scientific Instruments has published the poster, 'An evaluation of Fourier transform infrared (FTIR) microscopy: packaging, integrity, contamination, and stability (Pics) analysis of solid formulations in the pharmaceutical industry'.
In the current era of shrinking budgets, scientists are on the lookout for instrumentation that is capable of 'multi-tasking'.
FTIR microscopy fits this niche by performing routine analysis on tablets, caplets, and packaging materials in the pharmaceutical industry.
The ability to collect reflectance, transmission, and attenuated total reflectance (ATR) spectra is at the heart of this instrument's appeal.
This poster evaluates the utility that each of these techniques can provide to a pharmaceutical scientist by utilising Shimadzu's IRPrestige-21, in combination with the Aim-8800 microscope.
Capable of measuring in the near IR, mid IR and far IR ranges, the IRPrestige-21 features a highly optimised, high-energy throughput optical system that results in a signal-to-noise ratio of 40,000:1, while the Aim-8800 offers fast, accurate identification of microscopic contaminants, to enable comprehensive analysis with high-level data processing functions.
Results conclusively showed an ability to measure packaging thickness, identify contamination, determine the stability of actives, and the integrity of caplets and coatings identification.
