Bio-Rad Laboratories's product application guide, bulletin 5412A, provides information on a number of applications for Bio-Rad's new Proteon XPR36 protein interaction array system
The Proteon XPR36 protein interaction array system is a 6x6 multichannel surface plasmon resonance platform that enables automated analysis of up to 36 biomolecular interactions in one experiment.
All of the advantages of the ProteOn system: high-throughput, speed, kinetic response, and more are multiplied for research that involves large, broad, and complex studies such as results of hybridoma screening and ranking data that are compared with epitope mapping, specificity analysis, cross-reactivity determination.
In addition, multiplex analysis using XPR technology enables large amounts of complex data of being generated quickly so the data can be ready for comparison, seamlessly integrated, and easily categorised.
In this six-page application guide, four antibody characterisation and development protocols that demonstrate the versatility of the Proteon XPR36 system are briefly described.
The protocols are hybridoma screening and ranking, epitope mapping, kinetic analysis of antibody-antigen specificity, and determination of cross-reactivity of antibodies used in multiplex assays.
Bulletin 5412A is available either from a local Bio-Rad sales office or can be downloaded from the Bio-Rad Laboratories website.
