HTS plates for improved assay performance

Anachem is adding a new and revolutionary product range from MatriCal to its portfolio of lifescience research products. MatriPlates are 384 and 1536 well plates with a unique, patented well design that optimises all high-throughput assay applications, including fluorescence, chemiluminescence, colorimetric, and cell-based methods.

The plates maximise sample signal, improve ease of use with robotic systems, simplify assay miniaturisation and eliminate problems of vapour lock in the base of wells.

The secret to this improved performance is the distinctive MatriPlate well design: a truncated, inverted pyramid.

This enhances assay signal through better light transfer, providing up to ten times greater signal intensity compared to alternative plates.

The shape also helps direct pipette tips into the well base, allows liquid to flow smoothly into the bottom without trapping air bubbles and facilitates removal of the entire liquid, critical when the material is expensive and in limited supply.

Increased use of HTS technologies within drug discovery has made for more stringent quality control of plate dimensions.

All MatriCal plates are manufactured to the Society of Biomolecular Screening (SBS) specifications ensuring that they will 'fit' automated liquid handling and plate reading equipment without re-optimisation.

Use of patented materials and proprietary plastic formulations give exceptional uniformity, durability and stability.

Their rigidity guarantees that plates will not flex or bend when held by robotic grippers, avoiding spillages, cross contamination and mis-alignment of plate positioning on decks. The MatriPlate range includes over 30 lines of microwell plates designed for different applications.

These include black, white and clear plates, teflon impregnated polypropylene plates, patented low fluorescence material plates and chemical resistant plates.