Cytokine biochip arrays from Randox allow simultaneous detection of up to 12 cytokines and growth factors in a single undivided patient sample, giving more information from every microlitre
Cytokines are intercellular signalling molecules involved in regulation of the immune system.
These soluble proteins are activated in cases of inflammation, systemic response to injury and haemopoiesis.
Functions include activation of cell proliferation, cell migration and initiation of apoptosis.
Cytokines have been implicated in various pathological conditions including cardiovascular disease, cancer and autoimmune disease and concentrations may serve as markers of prognosis.
Biochip arrays utilise Biochip Array Technology, which is based on Elisa principles of sandwich or competitive immunoassays.
The 9x9mm biochip acts as a reaction platform, with up to 12 cytokine and growth factor specific antibodies attached at pre-defined sites on the surface.
Up to 12 analytes can be measured simultaneously using just 100ml of patient sample and either human serum or plasma can be tested.
Randox has a very strong R+D ethos and currently have more tests in development than any other diagnostic company in the world.
Three cytokine arrays are currently available and two more are planned for release before the end of the year.
