Assay Designs's Hsp70 high sensitivity EIA kit is for the accurate and specific quantification of as little as 90pg/mL of inducible Hsp70 in serum and plasma samples from human, mouse, and rat origin
Since its merger with Stressgen Bioreagents in 2005, the Assay Designs portfolio of products has included the full line of Stressgen brand kits and reagents, enabling researchers to investigate biological pathways involved in the cellular response to stress.
This Hsp70 assay does not significantly cross react with other Hsp70 family members such as Hsc70 (Hsp73), Grp78, DnaK (E coli), or Hsp71 (M tuberculosis) allowing for accurate and specific quantitation of Hsp70 in samples.
Assay Designs's Hsp70 high sensitivity EIA kit is said to be the only product commercially available that is validated for the measurement of circulating Hsp70.
This product has been specifically optimised for use with serum and plasma, but has not been extensively validated for use with other sample matrices.
The Hsp70 high sensitivity EIA kit features liquid colour-coded reagents and a pre-coated 96 well plate that save lab time and reduce error.
There is no need for cumbersome Western blot analysis of serum and plasma samples.
A simple dilution of samples in the supplied kit assay buffer allows for the higher throughput analysis of up to 39 samples in duplicate per 96 wells in just 4.5 hours.
As scientists we understand the critical nature of your research and take every step to ensure that our products meet the highest quality standards for sensitivity, specificity, and reproducibility so you do not have to repeat experiments.
Hsp70 is a molecular chaperone whose expression is induced upon exposure of the cell or organism to conditions of stress.
It prevents protein aggregation and promotes the refolding of proteins that become damaged in response to environmental insults, pathogens, and disease.
Its activity is essential for cellular survival and recovery under stress conditions, as well as for the maintenance of normal cellular function under non-stress conditions.
Hsp70 has been implicated to play a role in a variety of disease and physiological processes such as hyperthermia, hypertension, toxic exposure to chemical agents, hypoxia, ischemia, inflammation, autoimmunity, apoptosis, cancer, organ transplantation, and bacterial and viral infections.
Hsp70 is a key regulator of many normal physiological processes including aging, spermatogenesis, menstruation, and physical activity such as exercise.
The Assay Designs high sensitivity Hsp70 EIA kit is designed to evaluate and monitor Hsp70 in these processes, and provides a key research tool for the investigation of Hsp70's role in physiology and disease.
