Olympus has introduced its enzymatic creatinine assay, which is suitable for use across the range of Olympus diagnostic analysers.
The assay is intended for use for quantitative determination of creatinine in human serum, plasma and urine.
It utilises an enzymatic method to achieve greater accuracy, showing less interference to bilirubin and antibiotics.
The assay complements the current Jaffe method, providing increased accuracy of creatinine measurements for specific patients where potential interferents exist from diabetics, renal failure, liver failure and jaundice specimens.
The limit of detection for creatinine using serum settings on an Olympus AU640 analyser was established at 0.88umol/L.
This assay meets the NKDEP guidelines and will minimise errors in eGFR calculations.
The assay employs the same calibrators and controls as the current Jaffe method; however, to ensure optimal traceability, new set points for calibrator and target values, as well as ranges for control sera have been assigned.
Sold in a kit format, the reagent has improved on-board stability of 60 days and a calibration stability of 14 days for serum and 30 days for urine.
