Syngene has introduced its Chromascan range of cost-effective automated TLC plate readers for rapid and accurate documentation and analysis of non-radioactive thin-layer chromatography plates.
The range of Chromascan and Chromascan Lite both feature a high-resolution 16-bit, colour CCD camera inside a darkroom and with just a few mouse clicks, can in provide accurate results as thin-layer chromatography (TLC) plate images or chromatograms.
These GLP-compliant systems are compact enough to fit inside a fume hood and can be supplied with a PC, or can be connected to an existing laboratory PC.
The darkrooms for Chromascan and Chromascan Lite are designed with overhead UV (254nm and 365nm) and white lighting providing the flexibility to automatically image all fluorescent or visible TLC plates.
Only the Chromascan darkroom is computer-controlled and its camera has a motorised zoom lens with feedback.
To analyse the results, Chromascan users have the option to add Chromatools software to either system.
With Chromatools, researchers can use the software's effective pixels feature to generate publication quality 2D images of up to 5.5m pixels.
This means it is possible to separate close TLC spots and produce accurate results.
Chromatools software can automatically analyse TLC spots to generate Rf data or chromatogram peaks to provide quantitative information such as the percentage total activity for each peak, therefore reducing the time scientists spend performing manual calculations.