Cellexus has announced the availability of the 50-litre format of the Cellmaker Regular, a single-use, disposable bioreactor system.
The company said the 50-litre format provides increased ODs and improved yields of soluble protein when compared with flask-grown cultures.
Cellexus designed the system specifically for culture of pichia, E coli and algae cells.
Its availability follows the launch of the 8-litre system in October 2008 to enable further scalability.
The Cellmaker Regular range of products use Cellexusbags, which are single-use, disposable cell-culture bags allowing fast set-up times and eliminating lengthy cleaning protocols.
Whereas other disposable systems require shakers, rockers, rollers or large environmental chambers, the Cellmaker Regular range of products employ proprietary airlift technology to efficiently mix, aerate and maintain cell suspension.
The systems are simple, scalable and inexpensive to use.
The Cellmaker Regular Controller units enable precise management of temperature (15C to 45C), bag-pressure and flow of air and oxygen into the cell culture.
Accurate control of these parameters enables optimisation of culture growth and improved expression levels of soluble protein.
