The automated inline dilution of samples with Metrohm's complete system of hardware and software for ion chromatography (IC) provides accurate determinations of anions and cations.
To get accurate results in chromatography, the determined sample peak areas must be within the limits of the calibration, according to the company.
High ionic concentrations can overload the column.
The Metrohm system is claimed to meet both of these challenges.
In order to perform automated dilutions, the 850 Professional IC, the 858 Professional Sample Processor and the MagIC Net software are equipped with a magnetic stirrer and an 800 Dosino.
The latter aspirates a defined volume of undiluted sample and transfers it to the mixing vessel.
Subsequently, the dilution medium, which is generally ultra-pure water, is dosed into the mixing vessel.
After intensive stirring, the peristaltic pump of the sample changer transfers the sample to the injection valve of the IC.
Alternatively, the sample can be injected directly.
After the quantitation of the sample's constituents, the software verifies if the peak areas lie within the calibration range.
If this is the case, the next sample will be analysed.
If not, the software, after calculating the dilution factor, will re-analyse the sample after applying the appropriate dilution.
Whether the sample is diluted or directly injected, automated intelligent dilution ensures that peak areas are always within the limits of calibration.
