Sigma-Aldrich has announced the Hystem, a fully-customisable synthetic extracellular matrix (ECM) for stem-cell research.
Hystem offers researchers flexibility to tailor microenvironments for their cultured cells that mimic natural in-vivo conditions, optimising stem cell proliferation and differentiation.
Hystem was developed by Glycosan Biosystems and consists of hydrogel cell culture scaffolds that provide a complex, three-dimensional environment in which cells are able to proliferate, much as they would in vivo.
Composed of hyaluronic acid and denatured collagen, Hystem's synthetic matrix offers greater control of the cellular environment than ambiguous extracted ECM alternatives.
Hystem is available to researchers who want to customise their own attachment factors, ECM proteins and peptides, and who require an animal-component-free system with a minimal number of cell attachment sites.
Researchers requiring a large number of generalised cell-attachment sites for their stem-cell cultures will benefit from Hystem-C.
Hystem-HP is available for scientists planning to incorporate and gradually release growth factors into the stem cell environment.
All options are consistently formulated and well characterised for both in-vivo and in-vitro experimentation.
