Leica Microsystems has released a single molecule detection system that offers an integrated platform for the most common single molecule techniques, such as FLIM and FCS.
The Leica TCS SMD Series also provides the ability to perform the newer and more precise verification methods for molecule concentrations and interactions, FCCS (fluorescence cross-correlation spectroscopy) and FLCS (fluorescence lifetime correlation spectroscopy).
The Leica TCS SMD Series integrates hardware and software from Picoquant with the high-end confocal system Leica TCS SP5 II.
Researchers can now control a complete SMD experiment via one interface, the LAS AF software from Leica Microsystems.
The system is said to simplify complex SMD technologies.
Application wizards guide the user step by step through SMD experiments and maximise the reproducibility of data.
With the universal SMD raw data format, one and the same data file can be analysed in various ways, leading to quantification with maximum content.
Field upgrades of Leica TCS SP5 and SP5 II confocal systems to any of the Leica TCS SMD systems, FCS, FLIM and FLCS, are possible.