Raindance Technologies has expanded the capabilities of its Sequence Enrichment Solution to enable the re-sequencing of up to 20,000 PCR targets.
In addition, Raindance said it supports whole-genome-amplified samples for targeted re-sequencing.
The company said the enhancements would be attractive for researchers investigating rare variants in large populations that cause cancer and other diseases.
Raindance said it has expanded the content of its DNA primer library from 4,000 amplicons to 20,000 amplicons, while maintaining the precision provided by microdroplet-based PCR.
This will allow researchers to incorporate a broader range of content for their large-scale targeted re-sequencing studies and to broaden their view of the human genome.
The company said the expanded DNA libraries will be available in the first quarter of 2010 and can be ordered through Raindance sales channels and service providers.
Raindance also announced that it now supports the use of whole-genome-amplified DNA samples for sequence enrichment.
This capability will enable researchers to conduct studies with sample quantities that were previously too small for targeted re-sequencing.
Scientists can now perform whole-genomic amplification (WGA) on rare or small samples that have very low amounts of DNA, such as those found in tumour biopsies.