Oz Biosciences is launching of a design tool for Adenovirus and Adeno Associated Virus (AAV) applications.
Magnetofection transduction technology is a method that associates nucleic viruses with magnetic nanoparticles coated with cationic molecules.
The magnetic nanoparticles are made of iron oxide, which is fully biodegradable, coated with specific cationic proprietary molecules varying upon application.
Their association with the gene vectors (DNA, siRNA, ODN and virus) is achieved by salt-induced colloidal aggregation and electrostatic interaction.
Designed to increase virus infection, Adenomag is a reagent dedicated to enhance Adenovirus and AAV infection.
It allows the rapid concentration of all viral particles onto cells.
Adenomag improves virus infectivity with extremely low vector doses.
Thanks to its specific properties, Adenomag is suitable for infecting non-permissive cells.
No molecular biology processes or biochemical modifications are required.
Adenomag is a magnetic nanoparticles formulation optimised for Adenovirus and AAV based on the Magnetofection technology.
It increases transduction efficiency and accelerates the transduction process.
It is efficient for hard-to-infect and non-permissive cells.
Adenomag concentrates the viral dose onto the cells and synchronises cells adsorption/infection without modifications to the viruses.
