Agilent Technologies has introduced the Agilent 6150B series single-quadrupole liquid chromatograph/mass spectrometer (LC/MS).
The 6150B series is said to enable substantially higher sample throughput.
To match the speed of fast chromatography, including ultra-performance liquid chromatography (UHPLC) such as the Agilent 1290 Infinity platform, the 6150B series can scan at 10,000amu/second, while maintaining high data quality.
This is important to confirm identification of the correct compound in the complex reaction mixtures such as those found in drug discover synthesis.
The Agilent 6150B series is the first Agilent single-quadrupole LC/MS equipped with Agilent Jet Stream Technology, a sample-inlet design that uses super-heated sheath gas to focus the ion stream entering the mass spectrometer.
The benefit of this, according to the company, is enhanced sensitivity from a stronger signal with lower relative standard deviation at the limit of detection.
Jet Stream Technology has demonstrated the ability to provide efficient ionisation for a broader range of compounds than electrospray ionisation or atmospheric pressure chemical ionisation alone.
This can also increase sample throughput by minimising the need to rerun samples in multiple ionisation modes to look for differences.
The Agilent 6150B series joins two other single-quad LC/MS models in the Agilent line up: the 6120B, which is an easy-to-use instrument for applications such as confirming identities of impurities in a quality assurance/quality control laboratory; and the 6130B, which is ideal for quantitative analysis of compounds over a range of molecular weight.
Each Agilent 6100B series model can be upgraded to higher levels of performance as needs change.
