Phenomenex has introduced Clarity Oligo-MS columns for rapid and efficient liquid chromatography-mass spectrometry (LC/MS) characterisation and quality control of synthetic RNA and DNA.
Based on the company's core-shell particle technology, the C18 columns are claimed to deliver shorter run times that traditional media, along with increased resolution and sensitivity.
With the high resolving power of Clarity Oligo-MS, impurities in complex synthetic mixtures can be separated from the peak of interest in less than 10 minutes.
The columns, which are part of the Clarity Biosolutions portfolio, are packed with either 2.6um or 1.7um particles, enabling high efficiency on any HPLC or UHPLC platform.
The Clarity Oligo-MS 2.6um columns operate at reduced backpressures compared with other oligonucleotide-specific columns, delivering UHPLC performance on any LC instrument, and methods are easily transferable.
The columns are claimed to boost the performance of existing sub-2um methods on high-pressure systems.
