Shimadzu Scientific Instruments has introduced the LC-20AP preparative LC pump, which can be used for analytical, semi-prep and prep LC applications without changing pump heads.
The wide flow rate range (0.01-150mL/min) with high pressure tolerance (6,000lb/in2 up to 100mL/min and 4,350lb/in2 up to 150mL/min) makes it possible to use 50mmID x 250mmL 5um-particle size columns to achieve high-resolution and high-efficiency purification, and improve productivity by five to 10 times over previous models.
The flow rate accuracy and precision were improved by minimising dead volume in the pump heads and using higher resolution micro-stepping motor control so that the pump can be used at an analytical flow rate range, such as 1mL/min, with high reliability.
Overall productivity and quality of the purification has also been improved.
If configured as an analytical/prep system, a user can develop a method at analytical scale then immediately convert the method for prep scale.
Shimadzu said it provides a tool to easily convert methods between analytical and prep for support customers.
In addition, the LC-20AP pump can be used with Open Solution automated prep LC/MS software, which allows researchers to purify their compounds by simplifying the workflow in a walk-up environment.
LC-20AP also consumes 40 per cent less energy in comparison with the previous model thanks to a high-efficiency power supply and motor control electronics.
