Bioseek is to use its Biomap predictive human-disease models to screen Amylin's Phormol library, enabling it to discover peptides with a potential for treatment of a range of inflammatory conditions.
This collaboration follows similar agreements in recent years between the two companies involving peptide screening and related drug-discovery activities.
Biomap Systems are primary cell-based models of human-disease biology, designed to replicate the intricate cell and pathway interactions as they are observed in human pharmacology and toxicology.
Depending on their mechanism of action, drug compounds induce specific patterns of change in these systems that can be compared to a number of reference profiles in the Biomap Database.
Biomap provides early insight into human pharmacological and toxicological properties of compounds, including on- and off-target effects, dose responses and the discrimination of closely related compounds.
