Shimadzu has partnered with Cerno Bioscience to offer LCMS quadrupole systems along with Massworks software to enable users to improve data calibration for more accurate mass determination.
In conjunction with Shimadzu's LCMS solution software, the package utilises Cerno's patented MSIntegrity calibration technology to improve mass accuracy by up to 100 times, while achieving excellent spectral accuracy on unit mass resolution mass spectrometers.
With Shimadzu's LCMS system and Cerno's Massworks software, researchers can perform accurate compound identification through elemental composition prediction - a capability usually only available on high-resolution systems at higher cost, according to the companies.
Massworks improves the quality of data and formula prediction from Shimadzu's mass spectrometers.
Results from unit mass resolution instruments begin to approach predictions from accurate mass instruments.
In addition, spectral accuracy can be improved up to tenfold for accurate mass instruments.
Users can open and process the LCMS solution data from the native Shimadzu .lcd files from the LCMS-2010, LCMS-2020 and LCMS-IT-TOF instruments through Massworks and Cerno's Directread technology.
This saves time and disk space, reduces transcription errors and simplifies file management.
As Directread does not alter the original data, it assists compliance with common regulatory requirements such as GLP and the Food and Drug Administration's 21 CFR Part 11.