Fluidigm has announced that the autumn 2010 edition of its community newsletter is now available free to download from the company's website.
The community newsletter is a quarterly publication dedicated to providing readers with the most recent research, product updates and news featuring Fluidigm integrated fluidic circuit (IFC) technology.
Each issue provides new information of interest including new products, applications and customer advances to researchers involved with gene expression, SNP genotyping and sample preparation for next-generation sequencing.
In the autumn 2010 issue, researchers from the Molecular and Cell Biology Group at LGC describe their investigation into the applicability of using digital PCR to estimate absolute limits of detection and quantitation associated with the validation of traditional real-time PCR methods for analysis of genetically modified (GM) ingredients.
A paper from the Institute for Stem Cell Biology and Regenerative Medicine at Stanford University describes how the Fluidigm Biomark system was used to conduct single-cell gene expression analysis identifying factors important to oocyte maturation and using these findings to develop an improved culture system for the in vitro maturation of cumulus-free oocytes.
A poster from the National Cancer Institute (NCI) in Frederick, MD, US, describes how the organisation has accelerated its sample preparation to take full advantage of the high-throughput sequencing capacity from its next-generation sequencers.
NCI researchers used the Fluidigm Access Array system to amplify and tag, in parallel, 48 unique exons from two cancer-related genes in 60 cancer cell lines.
The amplicons were pooled and sequenced, identifying six mutations and a SNP from this high-throughput screen.
This research raises the potential for large-scale screens to identify mutations associated with cancer.
The autumn 2010 newsletter also provides abstracts describing, and providing links to, the latest application notes, product introductions, company news, events programme and educational webinars from Fluidigm.
