After a request from a customer, YMC has assembled two systems for the purification of interferon at its facilities in Dinslaken, Germany.
The two identical Kronlab systems are intended for the purification of interferon using a RPC-column with a binary gradient.
Each system comprises a binary high-pressure gradient pump (2,000ml/min at 125 bar) with a solenoid valve to apply the sample via the system pump.
They both have a module for pressure data acquisition and an air-bubble detection device on the sample line.
A four-way, two-position valve allows the column to be bypassed.
A multiple wavelength UV detector with DAD features ensures the detection of the target proteins.
The programmable fraction collector allows the use of different rack types for tubes or glass bottles.
The RPC-column (500 x 150mm ID) and its guard column (100 x 100mm ID) are mounted in the system using custom-designed stainless-steel racks.
During a visit to Germany, the customer took the opportunity to make some small changes to the system design and layout, to get first-hand information about the products and work of YMC Europe and to gain additional training on the software and system.
Kronlab provided the customer with detailed documentation of testing as well as qualification or support for IQ/OQ/PQ verification.
Individual, client-specific testing and acceptance criteria were incorporated on request.
Maintenance and service is provided by qualified scientists or engineers.