Dolomite has introduced the Mitos Double Chip Holder H, which allows direct coupling of microfluidic chips and is suitable for double emulsion research in the pharmaceutical and cosmetic sectors.
The connector allows direct interfacing of two microfluidic chips with accurate micro-channel to micro-channel connection via a precision perfluoroelastomer gasket.
Once aligned, the connection provides minimal disruption to the fluid flow.
In one application, this was demonstrated by the flow of a stream of 50-micron droplets from one chip to another, showing that standard chips can be used to generate double emulsions.
Designed for use with the Mitos Edge Connector 4-way, the Mitos Double Chip Holder H provides eight fluidic connections to 1.6mm OD tubing.
Quick to connect and disconnect, the Mitos Double Chip Holder H operates over a wide temperature range (-15C to +150C) and pressure range (up to 10 bar) and offers good chemical resistance allowing a range of solvents and chemicals to be used.
A key application of the Mitos Double Chip Holder H is the generation of double emulsions.
Double emulsions have many applications in nutrition, cosmetics and the pharmaceutical industry, for example, allowing an active ingredient or cell to be enclosed inside a protective outer shell.
Creating a double emulsion requires both hydrophobic and hydrophilic surfaces in different parts of the system, which in a single device can be complex and expensive to achieve.
The Mitos Double Chip Holder H is said to provide a simple, time efficient and cost-effective solution.
It allows direct coupling of a hydrophobic chip and a hydrophilic chip, enabling users to generate both water-oil-water and oil-water-oil droplets by simply switching the chips around.
