Waters has announced that it has entered into a non-exclusive co-marketing and reselling agreement with Premier Biosoft to advance lipidomics research.
Waters will offer Premier Biosoft's Simlipid informatics platform for sale with Waters' Acquity UPLC and high-resolution, exact-mass Synapt and Xevo mass spectrometers for lipid analysis.
Responding to the challenges set by leading lipid researchers, Waters' exact-mass UPLC/MS systems for lipid analysis combine ultra-performance LC and proprietary ion-mobility mass-spectrometry technology with advanced lipidomics informatics for comprehensive and rigorous lipid characterisation from complex biological samples.
Ion mobility, found only with Waters' Synapt mass spectrometers, brings an additional, orthogonal dimension of sample separation to lipid analysis.
This technology provides greater levels of specificity and class separation to lipid analysis, including the separation of isobaric/isomeric lipid species.
Waters' Centers of Innovation Program recognises and supports the research of leading scientists and institutions around the world in numerous application areas, including metabolomics and lipidomics.
Premier Biosoft's Simlipid augments the Waters UPLC - HDMSe (ion mobility - mass spectrometry) data by performing an exact mass precursor ion search to generate a list of lipid candidates, which are then ranked by comparing diagnostic product ions observed in the high-energy HDMSe data and structure specific in-silico fragment ions from the Simlipid database.
Interpretation of spectra has been made easy by annotating matched peaks with corresponding compounds.
Simlipid generates portable reports and images in different file formats such as XLS, CSV, HTML, JPEG and PNG to facilitate dynamic information sharing.
In addition, each structure is mined for its associated class, reaction, pathway and enzyme so that scientists don't waste time and money on laborious manual annotation.
