Cresset has announced the release of bioisostere software replacement tool FieldStere Version 3.0.
FieldStere is a software tool that uses Cresset's field-point technology, together with a database of molecular fragments, to help guide drug-discovery projects and generate new intellectual property.
Version 3.0 includes updates to the science and user interface.
FieldStere V3.0 now enables researchers using fragment-based drug-discovery protocols to grow initial leads computationally.
It works both on projects operating with protein crystallography support and on those without these resources, an area currently under supplied with computational techniques.
FieldStere uses molecular interaction with proteins as a core descriptor rather than 2D structure, enabling diverse active molecules to be described as similar.
FieldStere V3.0 is available as a desktop application or command line interface on Linux, Windows and now also on Mac machines.
Alternatively, FieldStere may be accessed through Cresset's Professional Services Division.
A free evaluation is available through the Cresset website.