Amsbio has announced the ClioCell - an ex-vivo device for removal of dying and dead cells.
Designed to improve the viability and quality of cell populations and their subsequent productivity, the system comprises super-paramagnetic nanoparticles which have been coupled with proprietary elements that bind to dead and dying cells and cell debris.
The resultant product selectively initiates dead-cell removal, emulating dead-cell clearance mechanisms which operate in-vivo to keep tissues functioning optimally.
The technology is claimed to be step-changing, providing new opportunities to optimise cell growth, culture and storage.
ClioCell is suitable for a range of diverse academic and industrial applications. The ability to selectively remove inhibitory or toxic dead cells using a simple and rapid procedure results in radically improved cell populations; specifically, with regard to viability antibody/protein yield and consequent functional efficacy.
The technology has been evaluated by several leading independent commercial and academic research institutions working on cell culture projects.
It has been successfully tested on many cell types, both human and mammalian.
Cliocell can be manufactured to cGMP grade and the Amsbio team has experience of many cell types, pre and post thaw applications and Big Pharma project work.
