Bio-Rad Laboratories has launched the SureBeads Magnetic Bead System, designed to offer a fast and easy alternative to agarose beads for immunoprecipitation (IP).
Researchers have traditionally used agarose beads to precipitate and enrich proteins prior to western blotting or mass spectrometry. But the process can be time-consuming and labour-intensive.
Because agarose beads are porous, the antibody can remain trapped inside the bead where it is unable to properly bind the protein of interest.
Magnetisation is faster and more convenient than centrifugation for sample precipitation and washing steps, but the price point can be prohibitive. The SureBeads System is designed to provide a solution.
SureBeads Protein A & G Conjugated Magnetic Beads are designed to work with the proprietary SureBeads 16-Tube Magnetic Rack.
This features a one-piece removable magnet strip to improve sample handling and eliminate repeated centrifugation steps, allowing researchers to achieve results up to six times faster.
“I have used magnetic bead-based systems for more than three years now, and the quality of the new SureBeads System is among the best in the field,” said Oliver Wueseke, PhD student at the Max Planck Institute for Molecular Cell Biology and Genetics in Dresden, Germany.
“The real innovation resides in the rack. The slideable magnet, preferred fixation of tubes in the rack, and spacing between tubes that allow easy access to the tube lids make the SureBeads System easy to handle, faster, and more convenient.“