Immunology and infectious diseases applications folder covering use of surface plasmon response (SPR) technology to help scientists unravel the mechanisms of infection is available on request
Biacore has announced the availability of a new clinical research applications folder pack.
This details how its sensor chip-based SPR technology is helping scientists to understand the complex biological mechanisms that play a role in the immune system and in the processes of infectious diseases.
The new folder pack explores immunology and infectious disease research, citing applications from peer-reviewed journals demonstrating the use of Biacore's SPR technology in areas as diverse as HIV research, parasitology, rheumatology, inflammation, immunogenicity studies and clinical trials.
The nature of the interaction between an invasive organism and its host is crucial to the outcome of the infection.
SPR technology provides detailed profiling information on the mechanisms of host/pathogen interactions for the development of new therapeutics and also to unravel the complexities of the regulation of the immune system. In addition, the technology is readily applicable for the analysis of molecular interactions associated with every aspect of the viral life cycle to facilitate vaccine and drug development.
A recent paper published in Trends in Microbiology (Vol 11, No 3, p101-144) 'Spying on HIV with SPR', has highlighted the significant role that Biacore SPR technology plays in the comprehensive investigations underway into HIV. Insights into the mechanisms of such complex pathogens are possible through rapid and reliable generation of accurate kinetic data and enable scientists to identify potential targets in the search for effective therapeutic agents. "Biacore's SPR technology has long been applied to the fields of immunology and infectious disease research, with a large body of peer reviewed papers published," commented Clive Seymour, VP and head of life science research unit. "With rapid analysis and no requirement for labels, interacting molecules are investigated in a near native state and activity closely reflects in vivo behaviour, increasing the pace of research into some of the greatest challenges facing science today." Biacore's new immunology and infectious diseases applications folder is available on request.
