Products have demonstrated a ten-fold increase in sensitivity over silica methodologies and are said to be suited for cutting edge research into small molecular weight and rare transcript analysis
DNA Research Innovations has launched its first products for RNA purification based on its highly sensitive ChargeSwitch technology.
These products - CST RNA purification kit (cells) and CST RNA purification kit (micro-tissue) - have demonstrated a ten-fold increase in sensitivity over silica methodologies and are highly suited for cutting edge research into small molecular weight and rare transcript analysis, the company claims.
Analysis of micro tissue and single cell samples is a rapidly growing market driven by fields such as cancer research and the emergence of new areas of interest such as interference RNA (RNAi).
In customer testing, the new ChargeSwitch RNA purification kits were found to purify high quantities of total RNA and to capture small molecular weight, rare and long transcript more effectively than leading silica based methods, it says.
In common with other ChargeSwitch methodologies, these kits avoid the use of enzyme inhibitors such as ethanol, organic solvents or chaotropic salts to provide a measurable improvement in downstream application performance.
"ChargeSwitch Technology provides a major improvement in the field of RNA transcript purification" said Jim Robinson from St James University Hospital, Leeds, UK. "The protocols are quicker, more consistent and approximately ten times more sensitive than other purification strategies".
"The launch of our first ChargeSwitch kits for RNA purification is another major milestone for DNA Research Innovations", added Simon Douglas, CEO of DRI.
"These products are very well positioned to take advantage of the new interest in the field of micro sample analysis and emerging fields such as RNAi".
The CST RNA purification kit (micro-tissue) and CST RNA purification kit (cells) both come in 50 preparation sets.
