Toolkit provides all the resins required to optimise reaction conditions for amine synthesis and purification using reductive amination
The Reductive Amination Toolkit provides all the resins required to optimise reaction conditions for amine synthesis and purification using reductive amination.
This reaction is a powerful tool routinely used in generating structurally diverse drug candidates.
The toolkit includes two resin-bound reducing agents, three scavengers and a comprehensive technical guide.
The combined use of a bound reducing agent plus appropriate scavenger enables chemists to generate products in excellent yield and purity, using simple filtration as the sole purification step at the end of the reaction.
