In recent years, the pH Stat method has been employed by many synthesis labs for a wide range of orgnic systhesis applications, especially in the specialised enzyme laboratories
Most enzymatic determination methods (eg, Lipase, Trypsin ) of the FIP Commission (Federation Internationale Pharmaceutique) employed in Pharmaceutical analysis, biology and medicines are protected as separate methods in the non-volatile memory of the 718 Stat Titrino from Metrohm.
The evaluation can take a relatively long time as both the intermediate results and the FIP standards determined are stored in a pushup result memory.
This means greater statistical reliability.
However, the compact 718 Stat Titrino offers you not only solutions to problems in the enzyme laboratory.
It is equally well suited to determanding control tasks and the kinetic investigations in the synthesis laboratory and pilot plant.
Whether pH or redox values have to be set or held, the 718 is the instrument of choice.
For every determination 500 data groups comprising of volume, time and measured value are stored and processed to a typical pH stat curve which can be viewed either on the attached printer or PC. The actual evaluation is performed in the 718 where the use of up to nine time windows allow the determination of the consumption per unit time between any two points on the curve.
With sensitive pH Stat applications, exothermic reactions are often unavoidable. If the temperature increases too rapidly, the Pt 100 temperature sensor records this and the 718 Stat Titrino stops the reagent addition until the temperature is again back in the acceptable temperature limits.
As a Dosimat dispenser is integrated into the 718, complex dispensing tasks involving sensitive chemicals can be solved with safety precautions against actual temperature and pH.
If one of these parameters reaches a critical value, the addition of a reactant can be shut off, held or interrupted. Should such an event occur during the night, the result printout alerts the operator to the misdemenor.
A new feature of the 718 is the doc mode which allows measured value ramps to be monitored.
If one wishes to increase the pH value linearly over a set period of time then this can be achieved by this mode.
Should any temperature surprise occur during this procedure then an alarm or switch to cool the system automatically is activated. Finally via the tip mode (TitratioProcedures), up to nine user methods, I/O commands, or wait times can be linked in a single method.
