This new technique, to be launched at Pittcon 2004, uses superheated water instead of organic solvents as the mobile phase for chromatographic runs
High temperature liquid chromatography (HTLC) specialist Selerity Technologies will be unveiling the latest developments in temperature control at Pittcon 2004 in Chicago.
Over the past 12 months, Selerity says it has firmly established itself as a leader in HTLC with the launch of Polaratherm.
The company will be demonstrating new chromatographic techniques and methodology involving temperature gradients at the annual US show.
Selerity will be launching a high temperature oven with a flame ionisation detector (FID).
This unique technique, and a first for a chromatography specialist, uses superheated water instead of organic solvents as the mobile phase for chromatographic runs. The FID is thereby used as a universal detector.
Also showing at Pittcon for the first time will be the recently launched Polaratherm, a total temperature controller comprising a standalone column compartment.
New features include the addition of fully automated software control to achieve greater productivity and laboratory efficiency.
Polaratherm is compatible and can be seamlessly integrated with any existing high performance chromatograph.
It is particularly suited for the chromatographer eager to economically maximise productivity by improving work results, enabling faster run times, and increasing efficiency.
Selerity will also display its Blaze columns.
With polydentate polymer protecting the silica surface, these columns are configured for HTLC to remedy previous deficiencies and minimise column degradation.
They safeguard silica particles against hydrolytic breakdown providing an efficient and stable column at high temperatures.
The Selerity Blaze polydentate phase protects the silanol groups against attacks.
The polymer attaches to the silica structure at a number of points forming a protective cap over the hydrolytically unstable siloxane groups. With a strong commitment to research and experimentation in the use of temperature as a separation variable, Selerity will be presenting a number of papers at Pittcon.
The topics will cover strong technical and application angles.
They will range from work undertaken on the stability of pharmaceutical ingredients under HTLC conditions and evaluation of different column performances.
Selerity also holds significant expertise in the development of techniques and methodologies in supercritical fluid chromatography (SFC).
In addition to introducing a new supercritical fluid chromatograph, Selerity will report on an easy-to-use SFC technique for the analysis of both fatty acids and the naturally occurring esters in a single run, using a flame ionisation detector.
