Software upgrade will save molecular biologists hours of repetitive work by replacing manual comparison of gel images with a variety of rapid automated band or spot matching methods
Accurate band matching in seconds Upgrade will save molecular biologists hours of repetitive work by replacing manual comparison of gel images with a variety of rapid automated band or spot matching methods.
Syngene, a manufacturer of image analysis solutions, has upgraded its new GeneTools Version 3.1 software.
The upgrade will save molecular biologists hours of repetitive work by replacing manual comparison of gel images with a variety of rapid automated band or spot matching methods and also includes a unique multi-layer gel analysis capability for high throughput screening.
With GeneTools Version 3.1, after the Autotrack Location function has found all the tracks and bands on a gel, the software produces a full image analysis in seconds. GeneTools Version 3.1 can determine if any bands in a selected track matches any other band on the gel according to position, molecular weight or Rf value.
The software is so sophisticated, the analysis can even be extended to dot blots or microtitre plates where the parameters are set to find positive or negative reactions.
Results are displayed in one window as a gel image alongside a dendrogram or comparison table and can be exported to Excel spreadsheets or text files for archiving or use in reports. The new multi-layer feature of GeneTools 3.1 will benefit users screening different DNA samples and markers on a gel, which has several rows of wells on one gel.
The software automatically analyses each row as if it were a separate gel thus allowing geneticists to save time and money by obtaining results from several small gels using one large gel and a single electrophoresis run.
Paul Ellwood, Syngene's sales and marketing director, explained: "The new matching and multi-layer capabilities of GeneTools Version 3.1 are fully GLP compliant so users can be assured their data will be secure.
We believe clinical or plant geneticists, as well as forensic scientists either using multi-layer gels in high throughput screening or performing hours of laborious yet essential comparisons of hundreds of DNA bands, will find these features invaluable for obtaining fast, accurate results."
