Shimadzu Scientific Instruments has announced that its Prominence high-performance liquid chromatography (HPLC) vials have been designed with superior glass and septa quality.
Prominence HPLC 1.5mL and 4mL sample vials use a PTFE/silicone septum, so their cleanliness is suitable for everyday applications and demanding LCMS analysis.
The septum is press-fit inside the vial cap without bonding agents, which is said to eliminate possible sample contamination.
The design also prevents an autosampler's needle from pushing the septum into the vial.
For high-throughout laboratories, a snap-cap version of the 1.5mL vial, using the same PTFE/silicone septum, is also available.
A 6mm opening in the 1.5mL vials is said to provide a better target for an autosampler's needle and makes filling easier and cleaner.
Uniformity of glass vial bottom thickness ensures consistent needle depth from run to run and is one of 14 manufacturing points strictly controlled by Shimadzu.
Prominence Low and Extra Low Adsorption clear glass vials are made from pharmaceutical Type I borosilicate glass, which provides low compound loss through adsorption or catalytic degradation.
Amber glass vials are made from Type I Class B glass.
Both of these vials have low reactivity, pH shift and leaching characteristics.
The Extra Low Adsorption vials are said to be ideal for mass spectrometry users or when working with micromolar concentrations or low sample volumes where the surface-to-volume effects are more pronounced.
Prominence HPLC vials are available in 1mL, 1.5mL, 4mL, 13mL, 200mL and 300mL sizes.
All Prominence HPLC vials have been tested for compatibility with each of Shimadzu's autosamplers.