Waters has brought out the Acquity UPLC H-Class System, which incorporates the Acquity Ultraperformance LC (UPLC).
This makes sub two-micron particle column technology more accessible to a broader range of industries, applications and operators.
Beyond improving chromatographic performance when running UPLC columns as well as fully supporting HPLC columns, the Acquity UPLC H-Class system closely emulates HPLC workflows, simplifying method transfer from HPLC to UPLC.
The introduction of Acquity UPLC H-Class allows organisations to standardise their approach to LC with a common technology platform that makes the future transition from HPLC to UPLC-based methods straightforward and practical - from product discovery through to product-release testing.
The answer to achieving UPLC performance and benefits without fundamentally modifying HPLC workflows came in the form of the Acquity UPLC H-Class's new quaternary solvent manager (QSM) and sample manager (SM-FTN), with flow-through needle design, thereby mimicking traditional HPLC system workflow.
The featured QSM and SM-FTN on the Acquity UPLC H-Class combine to enable the chromatographer to achieve high separation efficiency using sub two-micron particle separations at high pressures.
The result is the seamless upgrade of chromatographic capabilities.
Backed by a range of Acquity UPLC columns that includes three particle substrates in 11 chemistries, all of which are scalable between HPLC and UPLC particle sizes, the Acquity UPLC H-Class introduction is complemented by new Acquity UPLC Method Transfer Kits.
These new kits contain both UPLC and HPLC columns, with specified chemistry, and an Acquity UPLC Columns Calculator, all designed to take the guess work out of method transfer.
Method development and method validation kits ensure efficient method development and robustness.