Waters has introduced has introduced a line of low-adsorption sample vials certified for LC/MS/MS analyses where analytical sensitivity and accuracy are critical.
The Truview LCMS vials are designed for analyses where analyte concentrations are in the order of ng/ml or pg/ml.
The vials are manufactured under tight controls using a proprietary process that limits the concentration of free ions on the surface of the glass, lowering analyte adsorption.
Normally, during the manufacture of glass vials, free ions are deposited on the surface.
Problems occur when the ions are freed from the surface and enter the sample, raising the pH and exposing ion exchange sites on the glass to sample analytes that can bind to the glass.
The longer a vial awaits aspiration and injection of its contents, the greater the analyte adsorption.