The Patchliner is a robotic multi-channel patch clamp workstation for high quality cellular electrophysiology with increased throughput capabilities.
Nanion has established its entry level device for automated patch clamp, the NPC-1 Port-a-patch, and is now launching its second generation instrumentation, the NPC-16 patchliner.
The Patchliner is a robotic multi-channel patch clamp workstation for high quality cellular electrophysiology with increased throughput capabilities.
The system uses Nanion's microstructured glass chips and employs microfluidics to enable fast and precise perfusion.
High success rates in gigaseal formation and stable whole cell recording of 60-80% are routinely achieved.
The Patchliner not only allows the fast application of compounds in laminar flow channels (50ms, ideally suited for ligand gated channels), but even enables intracellular perfusion, so both sides of the cell membrane are accessible by pipetting robotics.
The Patchliner builds on the success of the Port-a-patch technology, offering vast experimental flexibility with high quality and increased throughput.
