The latest addition to the Warner Instruments product line is the soft lipid-assisted micro-injection (Slam) pipette.
The latest addition to the Warner Instruments product line is the soft lipid-assisted micro-injection (Slam) pipette.
These pipettes are designed to provide micro-injection capability without the need to impale or rupture the cell membrane.
Slam pipettes have a lipid coating on the tip which simply fuses with a cell membrane allowing the pipette contents to be non-invasively injected into the cell cytoplasm.
Material to be injected, which is inside the micropipette, gains access to the inside of the cell either by diffusion or by low pressure ejection.
In addition, the micropipette lipid transfers to the plasma membrane thereby permitting modification of the lipids in the plasma membrane by an entirely novel approach.
These techniques have been shown to work with a variety of cell types which are difficult or otherwise impossible to micro-inject.
The Slam micropipettes are disposable, individually sterilised and available in two tip sizes, 0.5 um and 1.0 um.
