Olympus is showing two new intravital research systems at the American Association for Cancer Research annual meeting in Washington DC
The OV100 intravital observation system is a complete, closed-chamber system for high-sensitivity, high-speed imaging of mice and other small laboratory animals from micro to macro levels of observation.
The optics for the OV100 fluorescence imaging system have been specially developed to offer ultra-high light gathering capacity, and feature a combination of high numerical apertures and long working distances.
The OV100 features a wide 114x to 1x magnification range for seamless imaging of the entire body down to the single cell level without disturbing the animal.
High-resolution fluorescence imaging can be correlated with other techniques such as MRI, Pet and CT scans.
The OV100 is also suitable for long-duration time-lapse observations and supports a wide range of image processing functions and other post-imaging analysis techniques.
The system's five parcentric, parfocal objectives are mounted on an automated turret and include a zoom lens with a magnification range of 1.6x to 16x.
The IV100 intravital laser scanning microscope has been optimised for collecting light from deep within tissue.
Exceptionally high spatial, temporal and multi-wavelength resolution combined with novel far-red and near-IR imaging probes make it possible to image subcellular detail of internal organs and disease processes.
Relying on Olympus's high-precision engineering technology that has made the company the world's foremost provider of endoscopes, the instrument allows minimally invasive intravital research imaging.
The system features ultra-slim MicroProbe lenses for high-resolution laser-scanned imaging of tissue and cells inside the body cavity of small laboratory mammals.
Users can select from three MicroProbe lenses, including two of the world's slimmest objectives (each 1.3mm in diameter), along with the company's full line of regular microscope objectives.
With a MicroProbe lens and the IV100's flexible observation angles, organs can be observed deep inside the body through minimally invasive keyhole surgery.
A wide range of fluorochromes including those compatible with near-IR 748nm lasers is available for deeper, less damaging observations.
Olympus provides a full range of comprehensive approaches to macro-to-micro level imaging of living whole animals, organs, tissues and cells.
In addition to the IV100 and OV100 systems, the company offers the MVX10, a fluorescence microscope that combines maximum detection sensitivity for macro-level imaging with a high-magnification zoom for viewing and recording fluorescence specimens at the cellular level.
