Caspase assay kits are optimised for high-throughput screening with features including one-step homogeneous assays, a convenient mix-and-read format, and highly sensitive fluorimetric components
Apoptosis, a programmed, cell-autonomous death process, plays important roles in a variety of physiological and pathological events.
These range from normal fetal development to diseases, such as cancer, organ failure and neurodegenerative diseases.
During apoptosis, caspases execute the disassembly of cellular components by proteolytic cleavage of a variety of substrates, such as poly-(ADP ribose) polymerase, DNA-dependent protein kinase (DNA-PK), topoisomerases, and protein kinase C delta4.
At least ten caspases have been discovered.
Some of these caspases identify and cleave a specific peptide substrate, while others recognize the same peptide substrate.
AnaSpec's line of EnzoLyte caspase assay kits are optimised for high-throughput screening.
HTS-optimized features include: one-step homogeneous assays, a convenient mix-and-read format, and highly sensitive fluorimetric components.
