Companies agree to co-market the rapid generation of monoclonal antibodies by AbD Serotec and Chimera Biotec's complementary Imperacer assay technology for ultra-sensitive antigen detection
Each company will offer the services of the other to its customers throughout the world-wide market.
The Imperacer technology combines the advantages of flexible and robust protein detection through Elisa with the exponential signal amplification typical for PCR.
Imperacer uses antibody-DNA conjugates as a substitute for the antibody-enzyme conjugate used in Elisa.
Amplifying the conjugated marker-DNA typically results in a 100-10,000-fold increase in sensitivity over enzyme-linked assays.
Imperacer is currently used in human and veterinary diagnostics, bio-pharmaceutical research, biological defense, and in the food, beverage, and cosmetics industries.
It is used for a wide variety of highly sensitive analytic applications such as pharmaceutical R+D, first-in human studies, virus detection, prion analysis, pharmacokinetic studies, detection of toxins in food and beverages, and quality assurance for cosmetics.
AbD Serotec uses Hucal Gold, a proprietary recombinant antibody library technology to select antibodies against any given antigen in record time.
The process is performed entirely in vitro, and no laboratory animals are involved.
Pre-adsorption and intelligent counter-screening during the antibody generation process is used to drive the selection towards the unique epitopes on the antigen.
This allows the selection and purification of highly specific antibodies in just eight weeks.
Rapid monoclonal antibody generation service using Hucal Gold is offered worldwide to researchers both from academia and industry.
"The high sensitivity of the Imperacer system demands highly specific antibodies to be effective, and many of our customers are seeking such antibodies for these assays," commented Jan Detmers, business development manager of Chimera Biotec.
"We believe that the AbD Serotec process is ideal for rapidly generating antibodies with the specificity our customers need in order for us to be able to develop the best assay."
