Koch Membrane Systems offers the Spirapro TFC SR3 and reverse osmosis spiral elements for pharmaceutical and fine chemicals applications
Koch Membrane Systems (KMS) offers its Fluid Systems Spirapro TFC line of SR3 and RO pharmaceutical and fine chemicals spiral elements.
The Spirapro elements significantly lower operating costs for a wide variety of applications, including selective rejection, desalting and organics concentration.
Ideally suited for desalting and separation of antibiotics and APIs, the Fluid Systems Spirapro TFC elements utilise a proprietary, polyamide thin-film composite membrane with a sanitary spiral-wound net outerwrap.
The molecular weight cut-off for the TFC SR3 is such that the membrane will pass monovalent salts like sodium chloride, yet provide high retention of multivalent ions and uncharged organic solutes.
Retention of sugars, such as lactose, typically exceeds 99 percent.
These elements can be useful for separating small molecules from chromatography effluent or other intermediate purification processes.
The TFC RO elements are ideal for concentrating compounds with a molecular weight of 100 to 2000Daltons such as antibiotics, radiopaque contrast agents and polypeptides.
These reverse osmosis elements are specifically designed to increase efficiency and reduce costs by providing high rejection at low pressure.
Typically, Fluid Systems Spirapro TFC RO elements achieve better than 99.95 percent rejection of protein and lactose and achieve chloride rejection of 99.3 percent.
Both TFC SR3 and TFC RO elements can be used to replace Nanomax membranes originally supplied by Millipore, or Desal membranes originally supplied by GE Osmonics, says Koch.
All element components pass USP Class VI toxicity testing guidelines.
The maximum operating pressure for all Fluid Systems Spirapro TFC elements is 600psi, while the actual operating pressure is dependent upon system flux rate as well as feed, recovery and temperature conditions.
These spiral elements are available in 3.8-inch and 7.9-inch diameters at the standard 38 and 40-inch lengths.
Feed channel spacers are available in the N1 (31mil) standard or the N2 (46mil) custom sizes.
Additionally, KMS offers a complete line of antiscalants, cleaners and maintenance chemicals for all Spirapro TFC membranes.
Kochtreato antiscalants and Kochkleeno membrane cleaners help prolong membrane life and reduce cleaning cycle time.
All KMS chemical formulations are carefully reviewed by the company's process engineers and polymer scientists to verify that they will provide excellent performance benefits, including physical and chemical compatibility with the membranes.