SupelMIP TSNA uses solid phase extraction (SPE) in a fast and cost-effective molecularly imprinted polymer technique with applications in testing of tobacco-specific nitrosamines in urine
MIP Technologies and Supelco announce the launch of a new solid phase extraction (SPE) product for the selective extraction of tobacco-specific nitrosamines (TSNAs).
The SupelMIP TSNA cartridge is selective for the tobacco specific nitrosamines: NNN, NNK, NAT, NAB.
Tobacco-specific nitrosamines (TSNAs) are a class of known carcinogens that are found only in tobacco products.
The TSNAs are created during fermentation, curing and burning of the tobacco leaf.
Exposure to TSNAs from tobacco products can be confirmed by their detection in, eg, urine.
Conventional methods used for sample preparation of TSNAs are very elaborate and time-consuming.
Extraction with the new TSNA SupelMIP is fast and cost effective and the total sample pre-treatment time is less than two hours.
The method is robust, recoveries achieved are higher than 90 percent and the clean extracts allow low detection levels with minimised matrix effects.
The SPE sorbents based on molecularly imprinted polymers have been developed by MIP Technologies.
SupelMIP is a trade mark of Supelco, which distributes the product worldwide.
"As the release of SPE products continues for difficult targets, we expect to establish molecular imprinting as the method of choice for such applications," said Christine Widstrand, VP sales and marketing at MIP Technologies.
"The high recoveries, speed and ease of extraction and elimination of traditional, labour-intensive extraction steps are hallmarks of the SupelMIP product family".
"With molecularly imprinted polymer technology, analysts can reach a level of sample prep extraction selectivity that could not be achieved by conventional means," said An Trinh, product manager, Supelco.
"With the widespread advent of mass spec technology, more and more methods are requiring lower limits of quantitation when analysing difficult and dirty sample matrices.
"Improvements in selectivity during sample preparation is absolutely critical.
"By merging the strengths of both organisations in this collaborative effort, a new generation of innovative molecularly imprinted polymers and applications will emerge."
