Onyx columns, which contain solid rods of fused silica, produce results at high flow rates with low backpressure, reducing run times over conventional columns
Phenomenex announces the addition of a new 50 x 2.0mm ID column to its Onyx monolith line.
The 30% smaller diameter column requires less sample volume and reduces solvent consumption.
The permeable media separates viscous biological samples that clog traditional columns, making Onyx ideal for drug metabolism studies in pharmaceutical companies and contract labs.
For fast gradient conditions, flow rates on the Onyx 2.0mm ID can be increased during re-equilibration without backpressure constraints, significantly reducing overall sample cycle times.
The increased speed makes the columns ideal for high-throughput applications.
Onyx columns are also available in 3, 4.6 and 10mm diameters.
"As research companies move toward optimizing their chromatographic processes, Onyx provides a strong platform for faster sample throughput," explained Jason Lam, brand manager for Phenomenex.
"With these new 2mm diameter columns, chromatographers can work with low sample concentrations while maintaining high sensitivity and speed - a benefit for fast LC-MS gradient methods".


