The 7000A triple quadrupole GC/MS is designed to make femtogram-level sensitivity and high-speed MRM accessible to a wide range of commercial and government users
Agilent Technologies has introduced a triple quadrupole gas chromatograph/mass spectrometer (GC/MS) and an updated triple quadrupole liquid chromatograph/mass spectrometer (LC/MS) at the American Society for Mass Spectrometry meeting.
Agilent emphasised that these mass spectrometers are "smashing sensitivity barriers".
The 6460 triple quadrupole LC/MS is a breakthrough system that lowers detection limits fivefold compared to previous instruments, breaking through the femtogram level for many compounds.
"The new 7000A brings the proven ruggedness of our best-selling Agilent 5975C single quadrupole GC/MS to a triple quadrupole system, suited for lower levels of detection and dirtier matrices," said Chris Toney, Agilent vice president and general manager, GC/MS and ICP-MS.
"Users no longer have to make do with research instruments adapted for their needs.
"We designed the 7000A from the ground up for routine, high-performance, high-throughput operation".
Like the 5975C single quadrupole GC/MS, the reliability of the 7000A triple quadrupole GC/MS is anchored by Agilent's proprietary, well-proven heated monolithic gold-plated hyperbolic quartz quadrupole analyser.
Time-consuming cleaning of quadrupoles is not required, and Agilent GC/MS systems hold highly stable tunes and methods for long intervals.
This stability also makes the Autotune function perform extremely well.
The 6460 triple quadrupole LC/MS delivers best-in-class sensitivity in a wide range of applications, thanks to proprietary Agilent Jet Stream thermal gradient focusing technology.
"In just two years, the 6400 triple quad LC/MS product line has demonstrated huge performance gains," said Gustavo Salem, Agilent vice president and general manager, LC/MS Division.
"Dramatic sensitivity gains, faster polarity switching, faster and more MRMs in a method, using either time segments or scheduling, and HPLC improvements are a few examples.
"The 6460 demonstrates Agilent's commitment to becoming a leader in the triple quad LC/MS market".
The new 6460's breakthrough design enhances nebulization and desolvation and reduces ion dispersion at conventional LC flow rates, delivering many more ions to the mass spectrometer.
The result is stronger signals with lower RSDs at the limit of detection.
The Agilent Jet Stream provides high sensitivity for conventional flow separations to complement the exceptional sensitivity of the HPLC-Chip/MS for nanoflow methods.
Ideal applications include trace level environmental or food contaminants, pharmaceutical compounds, metabolites and protein biomarkers.
