A simple, fast, selective and sensitive solid phase extraction (SPE) product has been developed for confirmation and quantitation of fluoroquinolone (FQL) residues in food samples
MIP Technologies and Supelco announce the launch of a new SupelMIP product for the selective extraction of FQLs.
A simple, fast, selective and sensitive SPE product has been developed for confirmation and quantitation of FQL residues in food samples.
The SPE phase has been developed for multi-residue extraction of FQLs and has been validated for sarafloxacin, norfloxacin, enrofloxacin and ciprofloxacin.
FQL's comprise a group of broad-spectrum antibacterial agents which are widely used in human medicine and to treat infections in farmed fish, shrimp, turkeys, pigs, calves and poultry.
The presence of this antibiotic class in the environment at sub-therapeutic levels can lead to multiple FQL-resistant bacterial strains.
When used to treat animals, FQLs may end up in the human food chain causing allergic reactions while at the same time encouraging development of resistant bacteria.
Monitoring these substance residues at trace levels is therefore regulated by law.
The EU has set strict maximum residue limits (MRLs), the values of which depend on the particular compound and matrix, eg, the MRL for enrofloxacin in bovine kidney is set at 200 micrograms per kilogram.
The USA, Canada and Japan have also set MRLs but for a more limited range of quinolones.
The four different FQL's; sarafloxacin, norfloxacin, enrofloxacin and ciprofloxacin were extracted from bovine kidney, milk and honey with high and reproducible recoveries.
The precision of the methods are high with a relative standard deviation (RSD) below ten percent for all compounds studied.
"SupelMIP SPE-Fluoroquinolones is a fast and straightforward SPE method using a molecularly imprinted polymer.
"With this simple, single SPE cartridge method, the same limits of quantitation level are reached as competitor methods which require use of multiple SPE cartridge steps," said Christine Widstrand, chief business officer at MIP Technologies.
"This new SPE phase provides added value to the customers by being a fast and simple multi-residue extraction product for FQLs," said An Trinh, product manager, Supelco.
The SPE sorbents based on molecularly imprinted polymers have been developed by MIP Technologies.
SupelMIP is a trademark of Supelco, the worldwide product distributor.
